微生物學科暨研究所 - 葉秀慧

專業技術:
分子病毒學及癌症生物學


研究介紹
  ◎目前進行研究
  1. Carcinogenic mechanisms of HBV related HCC
(1) Sex hormones, including androgen or estrogen, and microRNAs in regulating the gender difference of HBV related HCC.
(2) Sex hormones in liver biology, including metabolism, angiogenesis, and protein degradation.
(3) The mechanisms for hepatic stem cells to liver cancers.
(4) Targeted cancer therapy of HCC.
2. Basic virology research for the virus related infectious disease(s)
(1) Functional study for the phosphorylation of viral nucleocapsid proteins, including HBV and coronaviruses
(2) Study the pathogen(s) for new emerging infectious diseases
   
   
專利授權區
選擇性雄激素受體調節劑(SARMs):蕾莎瓦(Sorafenib)及其衍生化合物經由選擇性抑制肝細胞中雄激素受體訊息傳遞路徑活化已達到防止肝癌生長之功效


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體液內來自腫瘤基因組內病毒嵌入位點之交接獲重組核酸片段/序列可作為腫瘤癌症(或病毒引起疾病)臨床診斷的生物標記 Circulation juction or re-arranged nucleic acid fragements/sequences released form the viral i


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體液內來自腫瘤基因組內病毒嵌入位點之交接或重組核酸片段/序列可作為腫瘤/癌症(或病毒引起疾病)臨床診斷的生物標記


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可交易技術