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1. Carcinogenic mechanisms of HBV related HCC
(1) Sex hormones, including androgen or estrogen, and microRNAs in regulating the gender difference of HBV related HCC.
(2) Sex hormones in liver biology, including metabolism, angiogenesis, and protein degradation.
(3) The mechanisms for hepatic stem cells to liver cancers.
(4) Targeted cancer therapy of HCC.
2. Basic virology research for the virus related infectious disease(s)
(1) Functional study for the phosphorylation of viral nucleocapsid proteins, including HBV and coronaviruses
(2) Study the pathogen(s) for new emerging infectious diseases |