國立臺灣大學-技術交易網

用來評估化療反應與早期偵測的紅外線影像之影像對位演算法( LONGITUDINAL IMAGE REGISTRATION ALGORITHM FOR INFRARED IMAGES FOR CHEMOTHERAPY RESPONSE MONITORING AND EARLY DETECTION OF BREAST CANCERS)

刊登日期：2014/05/21

‧ 專利名稱	用來評估化療反應與早期偵測的紅外線影像之影像對位演算法( LONGITUDINAL IMAGE REGISTRATION ALGORITHM FOR INFRARED IMAGES FOR CHEMOTHERAPY RESPONSE MONITORING AND EARLY DETECTION OF BREAST CANCERS)
‧ 專利證書號	US 8,805,038 B2
‧ 專利權人	國立臺灣大學
‧ 專利國家 (申請日)	美國 (2011/06/30)
‧ 發明人	陳中明, 李嗣涔, 李婉柔, 張哲瑋, 簡鈺峻, 李佳燕,

技術摘要：

This algorithm provides a marker-free approach to establishing the pixel correspondence among the IR images taken at different times, which is the basis for quantitatively characterizing the variation of the heat energy and patterns pixel-wise on a breast surface. The idea is to use the corner points of the heat pattern and the branch points of the skeletons of the heat pattern on the body surface as the initial fiducial points for the longitudinal IR image registration. The Thin-Plate Spline technique is used to model the nonlinear deformation between two IR images taken at two different times. Mutual information between the TPS-transformed image and the target image is employed as the metric quantifying the quality of the longitudinal IR image registration. To optimize the registration, Nelder-Mead simplex method is used to locally modify the pairings of the fiducial points in the source and target IR images to maximize the mutual information.

聯繫方式

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