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 牛樟芝之抗癌活性物質、製備方法及其用途(An Anti-Cancer Active Substance from Antrodia Camphorata, Method for Preparing the same and Use Thereof)
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刊登日期：2014/05/21 |
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| ‧ 專利名稱 |
牛樟芝之抗癌活性物質、製備方法及其用途(An Anti-Cancer Active Substance from Antrodia Camphorata, Method for Preparing the same and Use Thereof) |
| ‧ 專利證書號 |
1415669
5752925
US 9,950,021 B2
EP2329816B1
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| ‧ 專利權人 |
國立臺灣大學 |
‧ 專利國家
(申請日) |
中國 (2010/09/30)
歐洲 (2010/11/22)
美國 (2010/11/24)
日本 (2010/11/25)
馬來西亞 (2010/11/25)
美國 (2013/01/16)
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| ‧ 發明人/PI |
蔣丙煌,林育蔚,
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| ‧ 單位 |
食品科技研究所
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| ‧ 簡歷/Experience |
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| 技術摘要 / Our Technology： |
An anti-cancer active substance from Antrodia Camphorata, produced from mycelium of Antrodia Camphorata by following steps: (1) culturing mycelium of Antrodia Camphorata by liquid fermentation; (2) extracting the thus-obtained mycelium with ethanol and concentrating the extracted solution to obtain an ethanol extract; (3) dissolving the ethanol extract in water, and extracting with equal volume of ethyl acetate to obtain ethyl acetate extract; (4) purifying the ethyl acetate extract by silica gel column chromatography using hexane/ethyl acetate gradient as the mobile phase to obtain an eluate fraction g; and (5) purifying the eluate fraction g by silica gel column chromatography using hexane/ethyl acetate gradient as the mobile phase to obtain a specific eluate fraction which could be purified further to obtain the anti-cancer active substance from Antrodia Camphorata.
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| 專利簡述 / Intellectual Properties： |
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聯繫方式 / Contact： |
| 臺大產學合作總中心 / Center of Industry-Academia Collaboration, NTU |
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| Email：ordiac@ntu.edu.tw |
電話/Tel：02-3366-9945 |
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