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牛樟芝之抗癌活性物質、製備方法及其用途(An Anti-Cancer Active Substance from Antrodia Camphorata, Method for Preparing the same and Use Thereof) |
刊登日期:2014/05/21 |
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‧ 專利名稱 |
牛樟芝之抗癌活性物質、製備方法及其用途(An Anti-Cancer Active Substance from Antrodia Camphorata, Method for Preparing the same and Use Thereof) |
‧ 專利證書號 |
1415669 5752925 US 9,950,021 B2 EP2329816B1
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‧ 專利權人 |
國立臺灣大學 |
‧ 專利國家
(申請日) |
中國 (2010/09/30) 歐洲 (2010/11/22) 美國 (2010/11/24) 日本 (2010/11/25) 馬來西亞 (2010/11/25) 美國 (2013/01/16)
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‧ 發明人 |
蔣丙煌, 林育蔚, |
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技術摘要: |
An anti-cancer active substance from Antrodia Camphorata, produced from mycelium of Antrodia Camphorata by following steps: (1) culturing mycelium of Antrodia Camphorata by liquid fermentation; (2) extracting the thus-obtained mycelium with ethanol and concentrating the extracted solution to obtain an ethanol extract; (3) dissolving the ethanol extract in water, and extracting with equal volume of ethyl acetate to obtain ethyl acetate extract; (4) purifying the ethyl acetate extract by silica gel column chromatography using hexane/ethyl acetate gradient as the mobile phase to obtain an eluate fraction g; and (5) purifying the eluate fraction g by silica gel column chromatography using hexane/ethyl acetate gradient as the mobile phase to obtain a specific eluate fraction which could be purified further to obtain the anti-cancer active substance from Antrodia Camphorata.
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聯繫方式 |
聯絡人:
研發處產學合作總中心 |
電話:
(02)3366-9949 |
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地 址:
10617臺北市大安區羅斯福路四段1號 禮賢樓六樓608室 |
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