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空間型藥物釋放結構及其製法
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刊登日期:2014/05/21 |
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‧ 專利名稱 |
空間型藥物釋放結構及其製法 |
‧ 公開號 |
201039868 US 2010-0285128 A1
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‧ 專利權人 |
國立臺灣大學 |
‧ 專利國家
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中華民國 (2009/05/06) 美國 (2009/08/11)
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‧ 發明人/PI |
段維新,郭書廷 ,段廷昱,施敦富,謝宜廷 ,
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‧ 單位 |
材料科學與工程學系
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‧ 簡歷/Experience |
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技術摘要 / Our Technology: |
一種空間型藥物釋放結構及其製法,其可加速藥物釋放的速度。在此結構中,少量藥物顆粒均勻的分散於一高鎖水性高分子材料所構成的基地中。基地具有複數個孔洞及連通此等孔洞之複數條通道。藉由此基地中仍具有部分水分的特性,胃酸會很容易進入此基地中,來與每個藥物顆粒的表面接觸,這會有利於藥物釋出,且可使得原來不易溶於胃酸中的藥物,能較快速的溶於胃酸中。
A space filled drug release structure and a method of manufacturing the same are disclosed. The structure is composed of a highly water-absorbing polymeric matrix and drug particles dispersed in the matrix. The matrix has pores and passages interconnecting the pores together. Because some water is present in the matrix, gastric acid can easily penetrate into the matrix to reach each drug particle. The surface of each drug particle is therefore possible to contact with the gastric acid. The drug releasing rate is therefore fast. Such structure is helpful for those drugs with low dissolution ability in the gastric acid.
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專利簡述 / Intellectual Properties: |
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聯繫方式 / Contact: |
臺大產學合作總中心 / Center of Industry-Academia Collaboration, NTU |
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Email:ordiac@ntu.edu.tw |
電話/Tel:02-3366-9945 |
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