專利公告 Patents
與細胞共列印之墨水材料
刊登日期:2019/07/25
技術摘要 / Our Technology:
本發明提供一種用於列印可承載細胞之建構物的生物墨水組,包含一含有生物可降解聚胺酯與生物高分子之生物墨水及一二價金屬離子溶液。該生物高分子係為明膠、瓊脂、海藻酸鹽、玻尿酸及其鹽、幾丁聚醣、或其任意組合。本發明亦提供一種利用該生物墨水組進行三維列印以製備可承載細胞之建構物的方法,以及一種墨水組成物用於細胞三維列印之用途。
Provided is a bioink set for printing cell-loadable constructs, including a bioink which contains biodegradable polyurethane and biological macromolecules, and a solution of divalent metal ions. The biological macromolecule is gelatin, agarose, alginate salt, hyaluronic acid and salt thereof, chitosan, and combinations thereof. Also provided are methods of preparing a cell-loadable construct by three-dimensional printing with the bioink set, and use of an ink composition for three-dimensional printing of cells.
Provided is a bioink set for printing cell-loadable constructs, including a bioink which contains biodegradable polyurethane and biological macromolecules, and a solution of divalent metal ions. The biological macromolecule is gelatin, agarose, alginate salt, hyaluronic acid and salt thereof, chitosan, and combinations thereof. Also provided are methods of preparing a cell-loadable construct by three-dimensional printing with the bioink set, and use of an ink composition for three-dimensional printing of cells.
聯繫方式 / Contact:
臺大產學合作總中心 / Center of Industry-Academia Collaboration, NTU
Email:ordiac@ntu.edu.tw
電話/Tel:02-3366-9945