|
 Liposome Delivery System for Hydrophilic Charged Compound
|
刊登日期：2022/09/22 |
|
|
|
|
|
| ‧ 專利名稱 |
用於親水帶電化合物的脂質奈米顆粒遞送系統 |
| ‧ 公開號 |
WO/2022/197988
202302072
US 20220296518 A1
|
| ‧ 專利權人 |
國立臺灣大學 |
‧ 專利國家
(申請日) |
美國 (2021/03/18)
PCT (2022/03/18)
中華民國 (2022/03/18)
美國 (2022/03/18)
|
|
|
| |
| ‧ 發明人/PI |
陳進庭,李佳穎,蔡翠敏,彭柏鈞,
|
| ‧ 單位 |
生化科技學系
|
| ‧ 簡歷/Experience |
|
|
| 技術摘要 / Our Technology： |
A lipid-based nanoparticle (LNP) with high DL ratio and normalized release. The LNP of the present invention comprises an outer lipid monolayer encapsulating a plurality of lipid-active pharmaceutical ingredient (API)-ion complexes, wherein each lipid-API-ion complex comprises a complex of anionic lipid, API and ion wherein the API comprises a positively charged form of an API and wherein the outer lipid monolayer of the LNP comprises neutral lipids. The present invention further comprises a method of preparation of the LNP of the present invention
|
| 專利簡述 / Intellectual Properties： |
|
| |
聯繫方式 / Contact： |
| 臺大產學合作總中心 / Center of Industry-Academia Collaboration, NTU |
|
| Email：ordiac@ntu.edu.tw |
電話/Tel：02-3366-9945 |
|
|
| |
|
| |
 |
專利行銷平台