Liposome Delivery System for Hydrophilic Charged Compound
  ‧ 專利名稱 用於親水帶電化合物的脂質奈米顆粒遞送系統
  ‧ 公開號 WO/2022/197988
US 20220296518 A1
  ‧ 專利權人 國立臺灣大學
  ‧ 專利國家
美國 (2021/03/18)
PCT (2022/03/18)
中華民國 (2022/03/18)
美國 (2022/03/18)
  ‧ 發明人/PI 陳進庭,李佳穎,蔡翠敏,彭柏鈞,
  ‧ 單位 生化科技學系
  ‧ 簡歷/Experience
技術摘要 / Our Technology:
A lipid-based nanoparticle (LNP) with high DL ratio and normalized release. The LNP of the present invention comprises an outer lipid monolayer encapsulating a plurality of lipid-active pharmaceutical ingredient (API)-ion complexes, wherein each lipid-API-ion complex comprises a complex of anionic lipid, API and ion wherein the API comprises a positively charged form of an API and wherein the outer lipid monolayer of the LNP comprises neutral lipids. The present invention further comprises a method of preparation of the LNP of the present invention

專利簡述 / Intellectual Properties:


聯繫方式 / Contact:
臺大產學合作總中心 / Center of Industry-Academia Collaboration, NTU 電話/Tel:02-3366-9945