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 一種拮抗介白素-6的寡胜肽(Oligopeptide antagonist of interleukin-6)
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刊登日期：2014/05/21 |
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| ‧ 專利名稱 |
一種拮抗介白素-6的寡胜肽(Oligopeptide antagonist of interleukin-6) |
| ‧ 專利證書號 |
US 7,202,218 B2
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| ‧ 專利權人 |
國立臺灣大學 |
‧ 專利國家
(申請日) |
美國 (2005/08/03)
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| ‧ 發明人/PI |
魏凌鴻,蘇振良,郭明良,
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| ‧ 單位 |
腫瘤醫學研究所
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| ‧ 簡歷/Experience |
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| 技術摘要 / Our Technology： |
The present invention provides an antagonist peptide of interleukin-6 (IL-6), wherein the peptide comprises a amino acid sequence which is selected from the group consisting of SEQ ID NO: 5, SEQ ID NO: 6 and SEQ ID NO: 7. The peptide of the invention is able to specifically bind IL-6R and compete for the binding of IL-6 to IL-6R, to block IL-6-induced signal transduction and therefore effectively inhibits IL-6-mediated antiapotopsis and angiogenesis, and further inhibits IL-6-mediated tumor growth.
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| 專利簡述 / Intellectual Properties： |
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| 相關圖片： |
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聯繫方式 / Contact： |
| 臺大產學合作總中心 / Center of Industry-Academia Collaboration, NTU |
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| Email：ordiac@ntu.edu.tw |
電話/Tel：02-3366-9945 |
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